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Hollow Fiber Filters
CleaSep hollow fiber filters are currently available in 17 different dimensions, suitable for R&D, pilot testing and commercial production. The filters demonstrate stable performance with reliable linear scalability when maintaining identical length but varying surface areas. Their material composition exhibits excellent chemical compatibility with various cleaning agents, ensuring safe and effective cleaning and disinfection of the filtration system. Compared to traditional PES, the modified PES membrane not only delivers higher flow rates, greater filtration capacities, shorter processing times and improved yields, but also features low protein-binding, low-blockage and easy-clean characteristics. The modification technology optimizes PES rigidity while enhancing membrane flexibility, enabling tolerance to higher process disturbances and shear rates.
Full Description
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Applied filters:
| Specs | Product | Optional Parameters | Availability | Operate |
|---|
Related Documents
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CleaSep Hollow Fiber Filters-Datasheet |
CleaSep Hollow Fiber Filters-Quick Usage Guide | CleaSep Hollow Fiber Filters-Technical Manual |
Features
- Fast and reliable lab-to-production linear scalability
- Modified PES material, lower protein binding and blockage, higher flow rate and filtration capacit
- Simple and reliable product design, no need for additional assembly and fixtures, easy to install and clean
- Narrow pore size distribution, high porosity, and high product recovery rate
- Good chemical compatibility and temperature resistance, can be cleaned and regenerated with a 1N sodium hydroxide aqueous solution at up to 80 ℃, and can withstand SIP sterilization
Applications
UF
- Purification and concentration of recombinant proteins/antibodies
- Purification, concentration, and dialysis of vaccines
- Concentration of virus, virus-like particles, virus vector
- Fractionation and concentration of nano materials and latex particles
- Rinsing, liquid exchange, and concentration of liposome
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Separation of natural products
MF
- Recovery and washing of cells and bacterial cells
- Clarification of fermentation broth and cell lysis buffer
Technical Parameters
|
Parts Material |
Hollow Fiber |
Modified Polyether Sulfone |
Potting |
Epoxy |
|
Filter Housing |
Polysulfone |
|
Sealing Ring |
Silicone |
|
Coupling |
Nylon+Fiber Glass(PI,PR)or Silicone(MN,LA) |
|
Port Plug |
Polypropylene(PI,PR)or Silicone(MN,LA) |
|
Protective Solution |
30wt%Glycerin+0.4wt%NaOH Solution |
|
Operating
|
Maximum Feed Pressure |
36psi/2.5bar@20℃ |
Maximum TMP |
Ultrafiltration 30psi/2.1bar@20℃
|
|
Operating Temperature |
≤40℃(Can Withstand SIP Sterilization) |
|
Operating pH Range |
1-14 |
|
Regulatory
|
Biosafety |
Meets USP<87>and FDA 21CFR Testing |
Dissolved Matter |
Meet the Requirements of ISO 10993-5(Cytotoxicity) |
|
Quality System |
Production under ISO9001 and GMP Quality Requirements |
|
Integrity |
100% Flux and Integrity Testing |
| Parameters of CleaSep Hollow Fiber Filters | |||||||||
| Type | Length (mm) |
Processing Capacity(L) |
Filtration Rating |
Number of Fibers | Area(m²) | ||||
| 0.5mm* | 1.0mm* | 1.5mm* | 0.5mm* | 1.0mm* | 1.5mm* | ||||
| miniLab | 320 | 0.3 | 10 kDa | 6 | 3 | 2 | 0.003 | 0.003 | 0.003 |
| 640 | 0.6 | 30 kDa | 6 | 3 | 2 | 0.006 | 0.006 | 0.006 | |
| miniLab+ | 320 | 0.7 | 50 kDa | 12 | 4 | 4 | 0.006 | 0.006 | 0.006 |
| 640 | 1 | 100 kDa | 12 | 4 | 4 | 0.012 | 0.012 | 0.012 | |
| Lab | 320 | 1 | 300 kDa | 36 | 18 | 10 | 0.018 | 0.018 | 0.015 |
| 640 | 2 | 500 kDa | 36 | 18 | 10 | 0.036 | 0.036 | 0.030 | |
| Lab+ | 320 | 5 | 750 kDa | 150 | 75 | 28 | 0.075 | 0.075 | 0.042 |
| 640 | 10 | 0.22μm | 150 | 75 | 28 | 0.150 | 0.150 | 0.084 | |
| Pilot | 320 | 15 | 0.45μm | 336 | 168 | 67 | 0.160 | 0.160 | 0.100 |
| 640 | 30 | 0.65μm | 336 | 168 | 67 | 0.330 | 0.330 | 0.200 | |
| 1150 | 50 | 336 | 168 | 67 | 0.600 | 0.600 | 0.360 | ||
| Pilot+ | 320 | 15 | 476 | 238 | 122 | 0.230 | 0.230 | 0.180 | |
| 640 | 30 | 476 | 238 | 122 | 0.470 | 0.470 | 0.360 | ||
| 1150 | 50 | 476 | 238 | 122 | 0.850 | 0.850 | 0.660 | ||
| Process | 320 | 120 | 3600 | 1700 | 700 | 1.800 | 1.700 | 1.050 | |
| 640 | 250 | 3600 | 1700 | 700 | 3.610 | 3.400 | 2.110 | ||
| 1150 | 500 | 3600 | 1700 | 700 | 6.500 | 6.130 | 3.790 | ||
*Fiber ID of Hollow Fiber Filters
FAQ